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gretel 09 May 2017

News of new collaboration [link] 8th May 2017Synbiosis and AAA Lab Equipment enter new collaborationCambridge, UK: Synbiosis, a long-established, expert manufacturer of automated microbiological systems, is delighted to announce a new development collaboration with high quality laboratory automation firm, AAA Lab Equipment, to integrate a ProtoCOL 3 colony counting system within an Irina automated plate feeder. The integrated system will allow microbiologists to load plates and count colonies on up to 500 plates in 90 minutes, improving throughput and accuracy in QC laboratories. Engineers at AAA Lab Equipment are working with Synbiosis to integrate the ProtoCOL 3 colony counter into their Irina automated plate feeding system. The plate feeder holds up to 500, 90mm plates in two carousels and automatically removes a plate from the carousel, reads and scans barcodes, removes the lid (if required) and will transfer the plate into an automated colony counter. Initially, AAA’s technical experts are re-engineering the plate feeder’s design for the ProtoCOL 3 system. Engineers at AAA are also working to ensure the plate feeder will transfer a plate to the ProtoCOL 3, where a high-resolution CCD camera and unique LED lighting will produce images of colonies as small as 43 microns (0.043mm). The ProtoCOL 3 software will count colonies and produce accurate results which will be automatically transferred to Excel or a LIMS system and plate images will be stored in an SQL database. Additionally, AAA’s software experts are programming the plate feeder to take account of the time a ProtoCOL 3 needs to count the colonies on each plate, to ensure the plate feeder’s loading arm replaces the plate into a second carousel after it has been analysed so that microbiologists know which plates have been read. Commenting on the new collaboration, Peter Krul, CEO of AAA Lab Equipment said: “We were approached by a large food microbiology testing facility in 2016 and asked if we could integrate an automated colony counter into our Irina plate feeder. Since then we have been working with the Synbiosis team for six months to re-engineer our plate feeder hardware and software for use with a ProtoCOL 3 colony counter. We know now that we can custom produce this cutting edge, walkaway technology for any food or environmental microbiology client requesting it.”To see how an integrated plate feeding and plate reading system will perform in real-time, click this link: [link] delighted to be collaborating with AAA Lab Equipment to help them develop a truly walk away, colony counting system” explains Kate George, Senior Divisional Manager at Synbiosis. “Integrating the ProtoCOL 3 into the Irina plate feeder will ensure quick, accurate generation of fully traceable data and will provide a significant competitive advantage for any high throughput microbiology testing facility using this exciting technology.”

gretel 08 May 2017

New product introduction SDI are consistently innovating - here's another one on the way from Atik. The technicals mean nothing to me, but maybe they do to others here:[link] the first Atik CMOS Camera PrototypeJo on May 3rd, 2017Between CEDIC and the NEAIC and NEAF shows earlier this year, this isn’t our best kept secret. But it’s now official – we’ve been working with a 16MP CMOS sensor, and we thought it about high time that we introduce you to our prototype development model.We’re taking the well-known Atik approach of designing the camera from the ground up specifically for astrophotography. It’s going to have features like a frame buffer and improved cooling in a body based on our tried and tested 4-series design. We’re integrating camera control into our renowned Capture software, along with the introduction of variable gain control exclusively for CMOS.You might be wondering how a CMOS astrophotography camera is going to vary from the CCD cameras in our range. We’re putting together some information on the technical differences between the two sensor technologies, and also what it means for your astrophotography in practical terms, so keep an eye out for those over the coming weeks.However, we will say now that what we love about this CMOS sensor is the real estate and resolution. We’ll also hold up our hands and say that CCDs are still the optimum technology for long exposure astrophotography. However, with 3.8µm pixels, this camera’s going to be a great match for shorter focal lengths and short exposure imaging.

gretel 02 May 2017

Big prospects for SDI's pH sensors Big article in Saturday's Times about the onset of robots and technology in farming - including the increasing usage of pH (acidity or alkalinity) measurement telling the farmer where and at what rate to apply fertiliser:[link] pH electrodes are of course "a large part" of subsidiary Sentek's business:[link]

gretel 28 Apr 2017

New highs today, and news [link] 27th April 2017NEW fluorescent peptide imaging application of PXi imaging systemCambridge, UK: Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its PXi multi-application imager is being used by scientists at the prestigious Freie Universtät Berlin for the new application of imaging fluorescent peptides on Western blots. Using the system is providing the researchers with a simple, sensitive method to detect cancer-linked transcription factors. In the Institute for Pharmacy at the Freie Universtät Berlin in Germany, scientists are using the PXi imaging system fitted with a 4 million pixel CCD camera, for imaging a peptide labelled with 5-carboxyfluorescein to fish out key interacting protein partners to essential transcription factors on Western blots. This drug discovery research may contribute to finding druggable targets for treating leukaemia and other life threatening cancers. Ee Lin Wong, a Ph.D. student in the Department of Pharmacy explained: “We work with a fluorescent peptide on Western blots but we can’t image our results using X-ray film because the fluorescence with this peptide can get so bright that it causes band saturation which over-exposes the film and ruins the results. Then we must start all over again with new film, which takes time and is frustrating.”Ee Lin added: “We chose the PXi because the system is compact, yet is more sensitive than film. This saves time as we can detect the proteins we’re looking for without having to keep repeating our fluorescent blots or use extra X-ray film. The best thing about the PXi is that the software is very fast and downloads images we can save to a USB stick in a format we can easily analyse and transfer into a file at exactly the right specifications for publication. This allows us to submit good quality figures more rapidly to scientific journals and is a great feature of the PXi system.”To find out more about the fluorescence imaging capabilities of the multi-functional PXi system, please click here: hxxp://www.syngene.com/pxi-pxi-touch“We’re always pleased to hear about new and exciting applications of our imaging technology,” stated Dr Martin Biggs, Sales Manager at Syngene.“The research at this prestigious German institute shows that the PXi imaging system is an excellent choice for drug discovery scientists looking to access sensitive detection of fluorescent peptides, as well as quickly and easily generate publication-quality formats of their important scientific data."

penhome 27 Apr 2017

Resistance around 27p? Looking at the long term chart, there seems to be a zone of resistance around 27p, so it could become quite interesting if it breaks above that with increasing volume.[link]

gretel 07 Apr 2017

"Revolutionary" new software product SDI introduce "revolutionary" new software (ThermoFisher are huge, with $17 billion+ turnover):[link] 5th April 2017Synbiosis introduces ThermoFisher Scientific Chromogenic ID Media SoftwareCambridge, UK: Synbiosis, a long-established, expert manufacturer of automated microbiological systems, is delighted to announce its Chromogenic ID software for use with Synbiosis colony counters now has a validated module for automatic identification of bacteria and yeasts on ThermoFisher Scientific’s Oxoid Chromogenic media. Using this revolutionary software allows microbiologists to rapidly and accurately identify microbes cultured on the world’s most commonly used media.The intuitive Chromogenic ID software module, guarantees that microbiologists using the digital colour imaging technology unique to the ChromoZona, ProtoCOL 3, and Protos 3 systems can with minimal training, automate precise identification of microorganisms on the Brilliance™ Candida, CRE and UTI ranges of ThermoFisher Scientific’s Oxoid chromogenic media. This not only saves time but also ensures that results are objective and consistent between scientists. analysing true to life colour plate images captured by ChromoZona, ProtoCOL 3 and Protos 3 systems, the software’s advanced algorithms can distinguish between similar shades of mauve, pink and blue colonies. This provides fast identification of microbes including Candida spp., carbapenem-resistant E. coli, Klebsiella spp., Enterobacter spp., Serratia spp., Citrobacter spp. Enterococcus spp., Proteus, Morganella and Providencia spp. on four different Brilliance agar plate types. collecting consistent data and reducing identification errors, the new Chromogenic ID software generates accurate results every time. These can be stored in a secure SQL database, making the software compliant with CFR 21 part 11 and easier to integrate into a GLP/GMP environment.To find out more about this innovative new Oxoid Chromogenic ID Media Software Module scientists can click the link: [link] chromogenic media is extensively used world-wide, yet distinguishing between different coloured colonies on these media can be problematic and depends on the subjective colour vision of the scientist” explains Kate George, Senior Divisional Manager at Synbiosis. “Utilising our incredible new software module to automatically analyse these well-known plates is a major advance which guarantees microbiologists everywhere efficient and accurate microbial identification.”

gretel 23 Mar 2017

News from Syngene [link] 21st March 2017G:BOX Chemi XX6 used to study effects of stressors on bacteria - research may contribute to identifying targets for new anti-microbials Cambridge, UK: Syngene, a world-leading manufacturer of image analysis solutions, is pleased to announce its G:BOX Chemi XX6 multi-application imager is being utilised by scientists at the University of Warwick to rapidly and accurately analyse how Gram positive bacteria react to stressors. This is providing information on phenotypic changes and may identify potential genetic targets, which could help in developing new anti-microbial therapies for drug-resistant bacteria.Researchers in the Department of Biomedical Sciences at the University of Warwick are using a G:BOX Chemi XX6 multi-application imaging system to study the changes that occur following exposure to stressors in the model Gram positive bacteria, Bacillus subtilis (a close relative of drug-resistant bacteria, such as Staphylococcus aureus)........Dr Emma Denham, Assistant Professor of Molecular Bacteriology at the University of Warwick explained: “B. subtilis expresses over 1500 non-coding RNAs and we want to determine what they are regulating and how they are doing it. As part of this research we’re using a G:BOX Chemi XX6 system to analyse chemiluminescent RNA and proteins, as well as image B. subtilis and E. coli colonies on 25 cm plates to identify interesting clones.”Emma continued: “We chose the G:BOX Chemi XX6 because it is the only analyser we tested that could cope with imaging bacteria on large plates, as well as Northern and Western blots and we haven’t yet found a fluorescence or chemi imaging application the G:BOX Chemi XX6 cannot perform.”

IOMINVESTCOM 06 Mar 2017

Re: SDI still good value imho Today's price action on the following chart shows how much it re-acted outside of the trending channel:-[link]

IOMINVESTCOM 06 Mar 2017

Re: SDI still good value imho Hi Gretel,Yes, you are right with your comments and there was hints of potential new deals soon but I could not resist to sell some at 29p this am. No issue with buying more back on weakness as I think you maybe able to trade this one as well as keep some of your lowest purchase price paid.atb

gretel 06 Mar 2017

SDI still good value imho For the year starting soon - even if they aren't upgraded after the upcoming year end - SDI are forecast to make 1.9p EPS.At 27p that's a P/E of only 14.2, so pretty good value despite the rise after the SCSW tip, even before any further acquisitions (which are highly likely).The SCSW article notes that SDI "could easily become a multibagger".

IOMINVESTCOM 06 Mar 2017

Banked some profit Used the SCSW article as reason to sell half & bank 40% profit leap from early Feb purchase.atb

IOMINVESTCOM 03 Mar 2017

Re: Hello gretel Hi Gretel,Spread seemed wide again today but all buys today going thru with SCSW due out tomorrow one week earlier than planned. Good to see a full recommendation on these!![link] a good weekend.atb

gretel 22 Feb 2017

Re: Hello gretel Enough time has probably passed to allow posting of SCSW's brief article on SDI in the most recent issue - "more in a future issue":[link] Digital Imaging18.75p Epic code: SDI(Sharewatch) Small but finally beginning to look well formed is Scientific Digital Imaging (SDI; 18.75p), which is a mini Judges lookalike with a ‘buy and build’ strategy in the scientific instrument space. Two recent deals since October ‘15 have added much needed scale. Smaller of the two was Sentek, a manufacturer of electrodes primarily for the measurement of pH and conductivity followed by Astles, which provides an imaging and dosing control system for the canning industry, where after the aluminium cans are pressed to remove any residues, they are cleaned before being sprayed with a protective coating. Other divisions, for instance, scan hospital scalpels when they are sterilised. Small niche with 80%+ of sales exported. Eps forecast is 1.7p with 1.9p next year. More in a future issue. Buy."

mantrova 20 Feb 2017

Re: Hello gretel Hi All and thanks IOMINVESTCOM, for the reminder on SCSW.In the SCSW Feb edition, SDI got the mention with an attached "BUY" of a further write-up in their March edition, which will be on Saturday 11th.The Feb mention certainly sparked quite a bit of interest, from which it understandably fell back somewhat, although I guess the "Full Monty" on March 11 will draw a much wider investor interest. I'm looking forward to whenever they say - particularly if it also relates to other matters, post the Feb coverage.m

gretel 20 Feb 2017

Moving up, and news Interesting to see the spread close to 2p and the price up despite two 50k sells this morning (they look like sells anyway). The obvious assumption has to be that there's buyers out there in the background.The below link/news may provide a perfect opening for ProReveal across the pond.As regulars will know, Ultraclean Systems is SDI's distribution partner and has already placed the device in hospitals over there.So, with that company now as announced yesterday being exclusively aligned to the giant Getinge Group, there must surely be more than an outside chance that ProReveal could now benefit as the perfect device to assist the instrument cleansing process.[link] link underlining the case as tech around the instrument space expands:[link] product development news from SDI's Synbiosis:[link] 15th February 2017NEW Chromogenic ID software from Synbiosis makes identifying microorganisms on HardyCHROM™ media quick and simpleCambridge, UK: Synbiosis, a long-established, expert manufacturer of automated microbiological systems, today announced its Chromogenic ID software for use with ChromaZona, ProtoCOL 3 and Protos 3 automated colony counters has been upgraded and validated for automatic identification of bacteria and yeast on Hardy Diagnostics' HardyCHROM™ media. Using this new software allows all microbiologists to rapidly generate accurate, objective microbial identification results.The new Chromogenic ID software module, developed in partnership with Hardy Diagnostics, ensures that with minimal training, microbiologists using ChromaZona, ProtoCOL 3, and Protos 3 systems can, at the touch of a button, identify microorganisms based on colour and morphology using a wide range of chromogenic media including: HardyCHROM™; CHROMagar™; Brilliance™ and Colorex™.Using intelligent algorithms to analyse life-like colour plate images captured by ChromaZona, ProtoCOL 3 and Protos 3 systems, the software is so advanced that it can distinguish even turquoise from steel blue colonies. This guarantees precise identification of common pathogens, including Listeriamonocytogenes, Salmonella spp., Shigella spp., methicillin resistant Staphylococcus aureus (MRSA), Cronobacter sakazakii, Candida spp. and E. coli. The Chromogenic ID software provides consistent data and reduces user misidentification errors. The instrument generates accurate results which can be stored in a secure SQL database. This means the software is compliant with CFR 21 part 11 and is ideal for integration into a GLP/GMP environment.To find out more about this innovative software, scientists should click the link: [link] Hardy, President of Hardy Diagnostics stated: “We are pleased that Synbiosis now has software that will analyse HardyCHROM, our line of chromogenic plates. This will represent a major advance in speed, efficiency, and cost savings for microbiologists using our chromogenic media.”Kate George, Senior Divisional Manager at Synbiosis added: “Accurately distinguishing between different coloured colonies on chromogenic agar depends on a scientist’s expertise. partnering with Hardy Diagnostics to develop and validate this revolutionary software we can now guarantee that microbiologists using Chromogenic ID software with HardyCHROM media will rapidly achieve accurate and standardised microbial identification in their laboratories, no matter what their skill level.”

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