I have asked this question before? Techno fox Now i am no expert, however as an investor in both companies and with both UK companies doing cutting edge research into the same area i could not help join up these dots, and as someone who has followed the technology of both for years, i have to ask this question, could Reneuron CTX exosome technology targeting this and other types of cancer be a very good or perfect fit for CTL019, this is not the first time i have joined up these Dots.[link]
Re; early but could be more good new... techno foxGiven the importance of John Mc Cain in the US, Could we see a speeded up trial of this combination of cutting edge gene technologies for Brain cancer treatment.extract from one of my last postsOne of the exciting things about this study is the number of T cell clones that get into the brain after CAR T-cell infusion, Dr. O' Rourke stressed. If we can devise strategies to get more in, and combine that with modifying the tumor microenvironment, we might see better clinical results." One possibility may be to combine CAR-T therapy with checkpoint inhibition, potentially using programmed cell death protein 1 (PD-1) or programmed death-ligand 1 (PD-L1) inhibitors, he suggests. A number of groups at Penn University are also actively carrying out research on the GBM tumor microenvironment, both in preclinical models and in patients.
Re; early but could be more good new... [link]
Re; wow early but could be more good news Techno fox sorry for not explaining why I thought the last post was significant for Oxford Bio, They supply the delivery system for ctl019, and this delivery system has now been shown it is capable of not only getting past the blood brain barrier but also deliver CTL019 in to a solid tumour, as a delivery system does this not open up the door for this delivery method to be used with other gene based technology.which could fight other age and related Brain conditions.
wow early but could be more good news [link]
Re: US investors opening & closing time Dave,Very many thanks for your comprehensive reply.. If this helps me in better t icing of my deals , I will let you know.Thanks again.Elbowroom
Re: US investors opening & closing time sorry forgot to turn those times into UK time there is a 5 hour difference so opening is give or take the pre session dealing ,is 9.30 U.S which is 14.30 UK ,and then close in new York at approx.16.00 or 21.30 here in the UK, but as there is a time gap right across the USA, trading continues after the official close in those state's affected most .Be HappyDav
US investors opening & closing time Answer The NYSE core trading session is between the hours of 9:30 a.m. to 40 p.m. Eastern Time. NYSE After Hours runs from 40 p.m. to 80 p.m. Eastern Time. The timetable for trading is as follows: NYSE Hours of Operation Pre-Opening Session 0330 - 0400 Opening Session 0400 - 0928 Market Order Freeze Period 0928 - 0930 Market Order Auction 0930 Core Trading Session 0930 - 1600 Closing Auction Freeze (MOC / LOC) 1558 - 1600 Closing Auction Run 1600 Closing Price Disseminated 1600 Extended Hours 160 - 2000 Limit Orders Cancelled 2000 The operating hours listed above are stated as Eastern Standard Time (EST) = GMT-5 / Eastern Daylight Time (EDT) = GMT-4. Most companies the USA now use twenty four hour platforms and can trade across the world ,which means you can trade by leaving buys or sells on the book , they can then strike a deal here or in the USA. That's why on some occasions you find that following morning the S/P can be out of tilt with the previous days closing price here in the UK . I Hope this helps,but I'm sure, others will have a different view regarding this question.BE Happy Dav
US investors At what time of day should we expect any USA investment to commence?Are there any rules preventing US investors leaving orders with their UK broker overnight ?
Something to read [link]
Re: Absolutely Gobsmacked You'd be more worried about his judgement if he didn't sell, after all, we know the market makers would drag it down after such a rise.
Novartis Results Link to CNBC.[link]
Re: Nasdaq (OXBDF), value OXB at 20p These articles are, I'm afraid, "old news" (as in last week) and will have no bearing on the share price's current travails.
Re: NEW ARTICLE: Trends and Targets for 18/0... At last, the article that tells you whether to invest in OXB or not. Someone had better let the FDA know about those trend lines so they make the right decision.
Re: Nasdaq (OXBDF), value OXB at 20p Yes elbowroom, I think there is a perception, probably justified, that the UK fails to capture the full value of the technologies developed in our academic sector. This is one of the reasons why Syncona has been set up as a long term investor for biotech and other biological science based companies and they explain this on their web site. My hunch is that they will succeed and they have certainly got off to a good start. Whilst I think OXB is too risky for me (although the potential rewards are very large) I am a shareholder in Syncona where the risk is reduced by having multiple companies in the portfolio, plenty of money to fund them and privileged access to many different technologies.